CHEM 3273 Synthesis of Blockbuster Drugs
Course Description
The course introduces the student to the modern organic chemistry and synthesis of selected modern blockbuster drugs. The synthesis of the ring systems is underpinned by theoretical organic chemistry. Application of the Woodward Hoffmann rules and the Baldwin ring closure rules will be discussed. The mechanistic features of important types of selected organic reactions in organic chemistry will also be discussed. Modern Mass and NMR spectrometric methods for determining the structures of intermediates and target drugs will also be presented.