Biological Chemistry
Nigel K. Jalsa - Lecturer
BSc. First Class Honours (Chemistry and Biochemistry) UWI 2005
PhD UWI 2010
1-868-662-2002, Ext. 83546, 83803 (Tel)
Selected Publications
- Jalsa, N. K. Tetrahedron Letters 2011, 52 (49), 6587-6590. Regioselective removal of the anomeric O-benzyl from differentially protected carbohydrates.
- Jalsa, N. K.. Popular Science 2012. Science Lesson Plan for Grades 6-8: Polymers.
- Subratti, A.; Lalgee, J. L.; Jalsa, N. K. Liquefied dimethyl ether (DME) as a green solvent in chemical reactions: Synthesis of O-alkyl trichloroacetimidates. Sustainable Chemistry and Pharmacy. 2018, 9, 46-50.
- Subratti, A.; Lalgee, J. L.; Jalsa, N. K. Synthesis and characteristics of sugar- phosphoramidates: A spectroscopic study. Tetrahedron Letters. 2018, 59, 3384-3388.
- Subratti, A.; Lalgee, J. L.; Jalsa, N. K. Liquified dimethyl ether (DME): A green solvent for the extraction of hemp (Cannabis sativa L.) seed oil. Sustainable Chemistry and Pharmacy. 2019, 12, Article 100144.
Research Interests
- *Development of catalysts with improved regio- and stereo-selectivity for various functional group transformations.
- *Synthesis of non-natural oligosaccharide analogues and evaluation of their utility as probes; and prophylactic medical therapies employing the principles of Metabolic Oligosaccharide Engineering.
- *Design and deployment of novel protecting groups which are regioselective, directing; robust to common synthetic transformation, but easily chemoselectively deprotected.
- *Synthesis of Peptide Nucleic Acids (PNAs) and the study of their unique physical, chemical and biological properties.
- *Synthesis of novel cyclodextrin derivatives and evaluation of their drug-delivery capabilities.