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183 prepared by the HEU Centre for Health Economics will be used to conduct interviews.To ensure that our interviews are conducted in a manner similar to those performed in the other countries a training workshop was organized. Professor Robert Stewart Institute of Psychiatry Kings College London a founding member of the 1066 Dementia Research Group trained persons who were selected to conduct the research.He is an internationally established epidemiologist and section head at the University of London who has conducted prevalence studies in numerous developing and developed countries. The study began in July 2014 and includes the following partici- pants 2000 persons randomly selected for interviews from all munici- palities in age ranges as follows 500 participants aged 60-69 years 500 aged 70-79 500 aged 80-89500 aged 90. Approach unique to Trinidad and Tobago First survey of a national population rather than a geographic catchment First such survey to adopt age-stratified sampling. Costing of dementia Expected Impacts Accurate assessment of the number of dementia cases in Trinidad and Tobago thereby allowing government and health and welfare organizations to plan adequate services. Identify the prevalence of dementia subtypes in Trinidad and possible risk factors Describe the living circumstances and care arrangements of people with dementia Quantify the economic cost of dementia for households. Raise awareness of dementia. More information about our research and future plans can be found at the following website httpwww.dartt.org.tt Basic Neuroscience Research My department of Preclinical Sciences introduced the MPhilPhD degree in Neuroscience in 2007. In 2014 it was with great pride that my postgraduate student Ashton Rogers presented his thesis for the first PhD degree in Neuroscience at The University of the West Indies. His thesis was entitled Diet Inflammation and the substantia nigra. In the late 80s I was a part of a team that demon- strated that inflammation could be playing a role in Parkinsons disease. This disorder is caused when a substantial number of dopamine producing neurons in a region known as the substantia nigra degenerate. For Ashton Rogers PhD we continued to examine the role of inflammation in the brain with new approaches.A single injection of lipopolysaccharide LPS induces dopamine DA cell death in the substantia nigra through an inflammatory mediated pathway. A high intake of calories is generally considered to provoke peripheral inflammation and could have consequences on the brain.We selected to investigate the influence of a high intake of calories in the presence of a low- grade inflammation which was induced by diluting the normal dose of lipopolysaccharide.Our findings indicate the addition of a sucrose solution to the diet accelerates inflammation and provokes a greater destruction to the dopamine neurons. Thus diet in combination with a minor inflammation in dopamine neurons which could occur in the early stages of Parkinsons disease could provoke a neurodegenerative cascade of events leading to an accelerated pathological state. Selected publications Davis G. N. Baboolal R. Mckay D. Pritchard and A. McRae. Antibodies to MHCI are associated with Alzheimers disease. AACC Annual Meeting July 15-19 2012 Los Angeles CA USA. Davis G. N. Baboolal S. Teelucksingh J. Ramesar and A McRae. Investigatingcognitive function in Type 2 diabetic patients using multiple testing instruments A case control study. West Indian Med.J. 2011 60 Suppl. 2 42 Baboolal N.S. G. Davis R. Stewart J. Ramesar and A. Mc Rae. Pioneering study on caregiver burden and dementia in the southern Caribbean. Alzheimers Dementia The Journal of the Alzheimers Association 2010 6 4 Supplement S335-S335 3.